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High-throughput optical sensing of peri-cellular oxygen in cardiac cells: system characterization, calibration, and testing

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) represent a scalable experimental model relevant to human physiology. Oxygen consumption of hiPSC-CMs has not been studied in high-throughput (HT) format plates used in pre-clinical studies. Here, we provide comprehensive charact...

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Detalles Bibliográficos
Autores principales: Li, Weizhen, McLeod, David, Ketzenberger, John T., Kowalik, Grant, Russo, Rebekah, Li, Zhenyu, Kay, Matthew W., Entcheva, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168216/
https://www.ncbi.nlm.nih.gov/pubmed/37163022
http://dx.doi.org/10.1101/2023.04.24.538133