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Alpha Synuclein Modulates Mitochondrial Ca(2+) Uptake from ER During Cell Stimulation and Under Stress Conditions

Alpha synuclein (a-syn) is an intrinsically disordered protein prevalent in neurons, and aggregated forms are associated with synucleinopathies including Parkinson’ disease (PD). Despite the biomedical importance and extensive studies, the physiological role of a-syn and its participation in etiolog...

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Detalles Bibliográficos
Autores principales: Ramezani, Meraj, Wagenknecht-Wiesner, Alice, Wang, Tong, Holowka, David A., Eliezer, David, Baird, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168219/
https://www.ncbi.nlm.nih.gov/pubmed/37163091
http://dx.doi.org/10.1101/2023.04.23.537965