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SARS-CoV-2 Nonstructural Proteins 3 and 4 tune the Unfolded Protein Response

Coronaviruses (CoV), including SARS-CoV-2, modulate host proteostasis through activation of stress-responsive signaling pathways such as the Unfolded Protein Response (UPR), which remedies misfolded protein accumulation by attenuating translation and increasing protein folding capacity. While CoV no...

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Detalles Bibliográficos
Autores principales: Davies, Jonathan P., Sivadas, Athira, Keller, Katherine R., Wojcikiewicz, Richard J.H., Plate, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168236/
https://www.ncbi.nlm.nih.gov/pubmed/37162862
http://dx.doi.org/10.1101/2023.04.22.537917