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Protein homeostasis from diffusion-dependent control of protein synthesis and degradation

It has been proposed that the concentration of proteins in the cytoplasm maximizes the speed of important biochemical reactions. Here we have used the Xenopus extract system, which can be diluted or concentrated to yield a range of cytoplasmic protein concentrations, to test the effect of cytoplasmi...

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Detalles Bibliográficos
Autores principales: Chen, Yuping, Huang, Jo-Hsi, Phong, Connie, Ferrell, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168264/
https://www.ncbi.nlm.nih.gov/pubmed/37162886
http://dx.doi.org/10.1101/2023.04.24.538146