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Rapid appearance of negative emotion during oral fentanyl self-administration in male and female rats
Opioid use disorder has become an epidemic in the United States, fueled by the widespread availability of fentanyl, which produces rapid and intense euphoria followed by severe withdrawal and emotional distress. We developed a new preclinical model of fentanyl seeking in outbred male and female rats...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168304/ https://www.ncbi.nlm.nih.gov/pubmed/37163074 http://dx.doi.org/10.1101/2023.04.27.538613 |