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Rapid appearance of negative emotion during oral fentanyl self-administration in male and female rats

Opioid use disorder has become an epidemic in the United States, fueled by the widespread availability of fentanyl, which produces rapid and intense euphoria followed by severe withdrawal and emotional distress. We developed a new preclinical model of fentanyl seeking in outbred male and female rats...

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Detalles Bibliográficos
Autores principales: Coffey, Kevin R., Nickelson, William, Dawkins, Aliyah J., Neumaier, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168304/
https://www.ncbi.nlm.nih.gov/pubmed/37163074
http://dx.doi.org/10.1101/2023.04.27.538613