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A small epitope shared by p53 and an unrelated protein upregulated after adenovirus infection

Cancers commonly harbor point mutations in TP53 that cause overexpression of functionally inactive p53 proteins. These mutant forms of p53 are immunogenic, and therefore present tantalizing targets for new forms of immunotherapy. Understanding how the immune system recognizes p53 is an important pre...

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Detalles Bibliográficos
Autores principales: Miciak, Jessica J., Bunz, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168313/
https://www.ncbi.nlm.nih.gov/pubmed/37162859
http://dx.doi.org/10.1101/2023.04.28.538733