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A small epitope shared by p53 and an unrelated protein upregulated after adenovirus infection
Cancers commonly harbor point mutations in TP53 that cause overexpression of functionally inactive p53 proteins. These mutant forms of p53 are immunogenic, and therefore present tantalizing targets for new forms of immunotherapy. Understanding how the immune system recognizes p53 is an important pre...
Autores principales: | Miciak, Jessica J., Bunz, Fred |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168313/ https://www.ncbi.nlm.nih.gov/pubmed/37162859 http://dx.doi.org/10.1101/2023.04.28.538733 |
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