Genetic context controls early microglia-synaptic interactions in mouse models of Alzheimer’s disease

Common features of Alzheimer’s disease (AD) include amyloid pathology, microglia activation and synaptic dysfunction, however, the causal relationships amongst them remains unclear. Further, human data suggest susceptibility and resilience to AD neuropathology is controlled by genetic context, a fac...

Descripción completa

Detalles Bibliográficos
Autores principales: Heuer, Sarah E., Keezer, Kelly J., Hewes, Amanda A., Onos, Kristen D., Graham, Kourtney C., Howell, Gareth R., Bloss, Erik B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168315/
https://www.ncbi.nlm.nih.gov/pubmed/37162819
http://dx.doi.org/10.1101/2023.04.28.538728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168315/
https://www.ncbi.nlm.nih.gov/pubmed/37162819
http://dx.doi.org/10.1101/2023.04.28.538728

Ejemplares similares