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Genetic context controls early microglia-synaptic interactions in mouse models of Alzheimer’s disease
Common features of Alzheimer’s disease (AD) include amyloid pathology, microglia activation and synaptic dysfunction, however, the causal relationships amongst them remains unclear. Further, human data suggest susceptibility and resilience to AD neuropathology is controlled by genetic context, a fac...
Autores principales: | Heuer, Sarah E., Keezer, Kelly J., Hewes, Amanda A., Onos, Kristen D., Graham, Kourtney C., Howell, Gareth R., Bloss, Erik B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168315/ https://www.ncbi.nlm.nih.gov/pubmed/37162819 http://dx.doi.org/10.1101/2023.04.28.538728 |
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