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Identification of a new Corin atrial natriuretic peptide-converting enzyme substrate: Agouti-signaling protein (ASIP)
Corin is a transmembrane tethered enzyme best known for processing the hormone atrial natriuretic peptide (ANP) in cardiomyocytes to control electrolyte balance and blood pressure. Loss of function mutations in Corin prevent ANP processing and lead to hypertension. Curiously, Corin loss of function...
Autores principales: | MacDonald, Bryan T., Elowe, Nadine H., Garvie, Colin W., Kaushik, Virendar K., Ellinor, Patrick T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168342/ https://www.ncbi.nlm.nih.gov/pubmed/37162877 http://dx.doi.org/10.1101/2023.04.26.538495 |
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