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Fission yeast CK1 promotes DNA double-strand break repair through both homologous recombination and non-homologous end joining

The CK1 family are conserved serine/threonine kinases with numerous substrates and cellular functions. The fission yeast CK1 orthologues Hhp1 and Hhp2 were first characterized as regulators of DNA repair, but the mechanism(s) by which CK1 activity promotes DNA repair had not been investigated. Here,...

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Detalles Bibliográficos
Autores principales: Cullati, Sierra N., Zhang, Eric, Shan, Yufan, Guillen, Rodrigo X., Chen, Jun-Song, Navarrete-Perea, Jose, Elmore, Zachary C., Ren, Liping, Gygi, Steven P., Gould, Kathleen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168346/
https://www.ncbi.nlm.nih.gov/pubmed/37162912
http://dx.doi.org/10.1101/2023.04.27.538600