Chimeric Antigen Receptor Macrophages Target and Resorb Amyloid Plaques in a Mouse Model of Alzheimer’s Disease

Substantial evidence suggests a role for immunotherapy in treating Alzheimer’s disease (AD). Several monoclonal antibodies targeting aggregated forms of beta amyloid (Aβ), have been shown to reduce amyloid plaques and in some cases, mitigate cognitive decline in early-stage AD patients. We sought to...

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Detalles Bibliográficos
Autores principales: Pan, Qiuyun, Yan, Ping, Kim, Alexander B., Xiao, Qingli, Pandey, Gaurav, Haecker, Hans, Epelman, Slava, Diwan, Abhinav, Lee, Jin-Moo, DeSelm, Carl J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168376/
https://www.ncbi.nlm.nih.gov/pubmed/37162824
http://dx.doi.org/10.1101/2023.04.28.538637

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168376/
https://www.ncbi.nlm.nih.gov/pubmed/37162824
http://dx.doi.org/10.1101/2023.04.28.538637

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