Deciphering the Differential Impact of Thrombopoietin/MPL Signaling on Hematopoietic Stem Cell Function in Bone Marrow and Spleen

Thrombopoietin (TPO) and its receptor MPL play crucial roles in hematopoietic stem cell (HSC) function and platelet production. However, the precise effects of TPO/MPL signaling on HSC regulation in different hematopoietic niches remain unclear. Here, we investigated the effects of TPO/MPL ablation...

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Detalles Bibliográficos
Autores principales: Lee, Sandy, Zhan, Huichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168386/
https://www.ncbi.nlm.nih.gov/pubmed/37162918
http://dx.doi.org/10.1101/2023.04.27.538580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168386/
https://www.ncbi.nlm.nih.gov/pubmed/37162918
http://dx.doi.org/10.1101/2023.04.27.538580

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