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The release of inhibition model reproduces kinetics and plasticity of neurotransmitter release in central synapses
Calcium-evoked release of neurotransmitters from synaptic vesicles (SVs) is catalysed by SNARE proteins. The predominant view is that, at rest, complete assembly of SNARE complexes is inhibited (‘clamped’) by synaptotagmin and complexin molecules. Calcium binding by synaptotagmins releases this fusi...
Autores principales: | Norman, Christopher A, Krishnakumar, Shyam S, Timofeeva, Yulia, Volynski, Kirill E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10168444/ https://www.ncbi.nlm.nih.gov/pubmed/37163032 http://dx.doi.org/10.21203/rs.3.rs-2700789/v1 |
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