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Higher tacrolimus trough levels and time in the therapeutic range are associated with the risk of acute rejection in the first month after renal transplantation

BACKGROUND: Tacrolimus trough levels (C(0)) are used in most transplant centres for therapeutic drug monitoring (TDM) of tacrolimus (Tac). The target range of Tac C(0) has been remarkably changed, with a target as low as 3–7 ng/ml in the 2009 European consensus conference and a target of 4–12 ng/ml...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi Van Anh, Nguyen, Huu Duy, Nguyen, Thi Lien Huong, Le, Viet Thang, Nguyen, Xuan Kien, Tran, Viet Tien, Le, Dinh Tuan, Ta, Ba Thang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169362/
https://www.ncbi.nlm.nih.gov/pubmed/37158838
http://dx.doi.org/10.1186/s12882-023-03188-0