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Cardiomyocyte-targeting exosomes from sulforaphane-treated fibroblasts affords cardioprotection in infarcted rats

BACKGROUND: Exosomes (EXOs), tiny extracellular vesicles that facilitate cell–cell communication, are being explored as a heart failure treatment, although the features of the cell source restrict their efficacy. Fibroblasts the most prevalent non-myocyte heart cells, release poor cardioprotective E...

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Detalles Bibliográficos
Autores principales: Papini, Gaia, Furini, Giulia, Matteucci, Marco, Biemmi, Vanessa, Casieri, Valentina, Di Lascio, Nicole, Milano, Giuseppina, Chincoli, Lucia Rosa, Faita, Francesco, Barile, Lucio, Lionetti, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169450/
https://www.ncbi.nlm.nih.gov/pubmed/37161563
http://dx.doi.org/10.1186/s12967-023-04155-x