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Aberrant m5C hypermethylation mediates intrinsic resistance to gefitinib through NSUN2/YBX1/QSOX1 axis in EGFR-mutant non-small-cell lung cancer
BACKGROUND: RNA 5-methylcytosine (m(5)C) modification plays critical roles in the pathogenesis of various tumors. However, the function and molecular mechanism of RNA m(5)C modification in tumor drug resistance remain unclear. METHODS: The correlation between RNA m(5)C methylation, m(5)C writer NOP2...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169458/ https://www.ncbi.nlm.nih.gov/pubmed/37161388 http://dx.doi.org/10.1186/s12943-023-01780-4 |