Aberrant m5C hypermethylation mediates intrinsic resistance to gefitinib through NSUN2/YBX1/QSOX1 axis in EGFR-mutant non-small-cell lung cancer

BACKGROUND: RNA 5-methylcytosine (m(5)C) modification plays critical roles in the pathogenesis of various tumors. However, the function and molecular mechanism of RNA m(5)C modification in tumor drug resistance remain unclear. METHODS: The correlation between RNA m(5)C methylation, m(5)C writer NOP2...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yueqin, Wei, Jingyao, Feng, Luyao, Li, Ouwen, Huang, Lan, Zhou, Shaoxuan, Xu, Yingjie, An, Ke, Zhang, Yu, Chen, Ruiying, He, Lulu, Wang, Qiming, Wang, Han, Du, Yue, Liu, Ruijuan, Huang, Chunmin, Zhang, Xiaojian, Yang, Yun-gui, Kan, Quancheng, Tian, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169458/
https://www.ncbi.nlm.nih.gov/pubmed/37161388
http://dx.doi.org/10.1186/s12943-023-01780-4

Ejemplares similares

Ejemplares similares