Cargando…

IRAK4 inhibition: an effective strategy for immunomodulating peri-implant osseointegration via reciprocally-shifted polarization in the monocyte-macrophage lineage cells

BACKGROUND: The biomaterial integration depends on its interaction with the host immune system. Monocyte-macrophage lineage cells are immediately recruited to the implant site, polarized into different phenotypes, and fused into multinucleated cells, thus playing roles in tissue regeneration. IL-1R-...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Juan, Li, Jia, Xu, Antian, Xu, Yangbo, He, Fuming, Mao, Yingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169473/
https://www.ncbi.nlm.nih.gov/pubmed/37158847
http://dx.doi.org/10.1186/s12903-023-03011-0