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Hypoxia regulates adipose mesenchymal stem cells proliferation, migration, and nucleus pulposus-like differentiation by regulating endoplasmic reticulum stress via the HIF-1α pathway

OBJECTIVE: Hypoxia can promote stem cell proliferation and migration through HIF-1α. Hypoxia can regulate cellular endoplasmic reticulum (ER) stress. Some studies have reported the relationship among hypoxia, HIF-α, and ER stress, however, while little is known about HIF-α and ER stress in ADSCs und...

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Detalles Bibliográficos
Autores principales: Wu, Jianxin, Yu, Lei, Liu, Yi, Xiao, Bing, Ye, Xiaojian, Zhao, Hong, Xi, Yanhai, Shi, Zhicai, Wang, Weiheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169485/
https://www.ncbi.nlm.nih.gov/pubmed/37158945
http://dx.doi.org/10.1186/s13018-023-03818-1