Determination of the microscopic acid dissociation constant of piperacillin and identification of dissociated molecular forms

For amphoteric ß-lactam antibiotics, the acid dissociation constant (pK (a)) is a fundamental parameter to characterize physicochemical and biochemical properties of antibiotics and to predict persistence and removal of drugs. pK (a) of piperacillin (PIP) is determined by potentiometric titration wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Guoao, Wang, Yaling, Sun, Chengyi, Liu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169600/
https://www.ncbi.nlm.nih.gov/pubmed/37179774
http://dx.doi.org/10.3389/fchem.2023.1177128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169600/
https://www.ncbi.nlm.nih.gov/pubmed/37179774
http://dx.doi.org/10.3389/fchem.2023.1177128

Ejemplares similares