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Determination of the microscopic acid dissociation constant of piperacillin and identification of dissociated molecular forms
For amphoteric ß-lactam antibiotics, the acid dissociation constant (pK (a)) is a fundamental parameter to characterize physicochemical and biochemical properties of antibiotics and to predict persistence and removal of drugs. pK (a) of piperacillin (PIP) is determined by potentiometric titration wi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169600/ https://www.ncbi.nlm.nih.gov/pubmed/37179774 http://dx.doi.org/10.3389/fchem.2023.1177128 |