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Therapeutic targeting of anoikis resistance in cutaneous melanoma metastasis

The acquisition of resistance to anoikis, the cell death induced by loss of adhesion to the extracellular matrix, is an absolute requirement for the survival of disseminating and circulating tumour cells (CTCs), and for the seeding of metastatic lesions. In melanoma, a range of intracellular signall...

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Detalles Bibliográficos
Autores principales: Neuendorf, Hannah M., Simmons, Jacinta L., Boyle, Glen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169659/
https://www.ncbi.nlm.nih.gov/pubmed/37181747
http://dx.doi.org/10.3389/fcell.2023.1183328