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Role and mechanism of FOXG1-related epigenetic modifications in cisplatin-induced hair cell damage

Cisplatin is widely used in clinical tumor chemotherapy but has severe ototoxic side effects, including tinnitus and hearing damage. This study aimed to determine the molecular mechanism underlying cisplatin-induced ototoxicity. In this study, we used CBA/CaJ mice to establish an ototoxicity model o...

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Detalles Bibliográficos
Autores principales: Mu, Yu-rong, Zou, Sheng-yu, Li, Ming, Ding, Yan-yan, Huang, Xiang, He, Zu-hong, Kong, Wei-jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169754/
https://www.ncbi.nlm.nih.gov/pubmed/37181652
http://dx.doi.org/10.3389/fnmol.2023.1064579