In situ continuous Dopa supply by responsive artificial enzyme for the treatment of Parkinson’s disease

Oral dihydroxyphenylalanine (Dopa) administration to replenish neuronal dopamine remains the most effective treatment for Parkinson’s disease (PD). However, unlike the continuous and steady dopamine signaling in normal neurons, oral Dopa induces dramatic fluctuations in plasma Dopa levels, leading t...

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Detalles Bibliográficos
Autores principales: Fang, Xiao, Yuan, Meng, Zhao, Fang, Yu, Aoling, Lin, Qianying, Li, Shiqing, Li, Huichen, Wang, Xinyang, Yu, Yanbin, Wang, Xin, Lin, Qitian, Lu, Chunhua, Yang, Huanghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169781/
https://www.ncbi.nlm.nih.gov/pubmed/37160866
http://dx.doi.org/10.1038/s41467-023-38323-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169781/
https://www.ncbi.nlm.nih.gov/pubmed/37160866
http://dx.doi.org/10.1038/s41467-023-38323-w

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