Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting

Chimeric antigen receptors (CARs) and synthetic Notch (synNotch) receptors are engineered cell-surface receptors that sense a target antigen and respond by activating T cell receptor signaling or a customized gene program, respectively. Here, to expand the targeting capabilities of these receptors,...

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Detalles Bibliográficos
Autores principales: Ruffo, Elisa, Butchy, Adam A., Tivon, Yaniv, So, Victor, Kvorjak, Michael, Parikh, Avani, Adams, Eric L., Miskov-Zivanov, Natasa, Finn, Olivera J., Deiters, Alexander, Lohmueller, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169838/
https://www.ncbi.nlm.nih.gov/pubmed/37160880
http://dx.doi.org/10.1038/s41467-023-37863-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169838/
https://www.ncbi.nlm.nih.gov/pubmed/37160880
http://dx.doi.org/10.1038/s41467-023-37863-5

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