Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components

In terms of its relative frequency, lysine is a common amino acid in the human proteome. However, by bioinformatics we find hundreds of proteins that contain long and evolutionarily conserved stretches completely devoid of lysine residues. These so-called lysine deserts show a high prevalence in int...

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Detalles Bibliográficos
Autores principales: Kampmeyer, Caroline, Grønbæk-Thygesen, Martin, Oelerich, Nicole, Tatham, Michael H., Cagiada, Matteo, Lindorff-Larsen, Kresten, Boomsma, Wouter, Hofmann, Kay, Hartmann-Petersen, Rasmus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169902/
https://www.ncbi.nlm.nih.gov/pubmed/37160462
http://dx.doi.org/10.1007/s00018-023-04782-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10169902/
https://www.ncbi.nlm.nih.gov/pubmed/37160462
http://dx.doi.org/10.1007/s00018-023-04782-z

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