Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface

Many secretory enzymes acquire essential zinc ions (Zn(2+)) in the Golgi complex. ERp44, a chaperone operating in the early secretory pathway, also binds Zn(2+) to regulate its client binding and release for the control of protein traffic and homeostasis. Notably, three membrane transporter complexe...

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Detalles Bibliográficos
Autores principales: Amagai, Yuta, Yamada, Momo, Kowada, Toshiyuki, Watanabe, Tomomi, Du, Yuyin, Liu, Rong, Naramoto, Satoshi, Watanabe, Satoshi, Kyozuka, Junko, Anelli, Tiziana, Tempio, Tiziana, Sitia, Roberto, Mizukami, Shin, Inaba, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170084/
https://www.ncbi.nlm.nih.gov/pubmed/37160917
http://dx.doi.org/10.1038/s41467-023-38397-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170084/
https://www.ncbi.nlm.nih.gov/pubmed/37160917
http://dx.doi.org/10.1038/s41467-023-38397-6

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