Cargando…
Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface
Many secretory enzymes acquire essential zinc ions (Zn(2+)) in the Golgi complex. ERp44, a chaperone operating in the early secretory pathway, also binds Zn(2+) to regulate its client binding and release for the control of protein traffic and homeostasis. Notably, three membrane transporter complexe...
Autores principales: | Amagai, Yuta, Yamada, Momo, Kowada, Toshiyuki, Watanabe, Tomomi, Du, Yuyin, Liu, Rong, Naramoto, Satoshi, Watanabe, Satoshi, Kyozuka, Junko, Anelli, Tiziana, Tempio, Tiziana, Sitia, Roberto, Mizukami, Shin, Inaba, Kenji |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170084/ https://www.ncbi.nlm.nih.gov/pubmed/37160917 http://dx.doi.org/10.1038/s41467-023-38397-6 |
Ejemplares similares
-
Author Correction: Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface
por: Amagai, Yuta, et al.
Publicado: (2023) -
Zinc regulates ERp44-dependent protein quality control in the early secretory pathway
por: Watanabe, Satoshi, et al.
Publicado: (2019) -
A virtuous cycle operated by ERp44 and ERGIC-53 guarantees proteostasis in the early secretory compartment
por: Tempio, Tiziana, et al.
Publicado: (2021) -
Protocol for synthesis and use of a turn-on fluorescent probe for quantifying labile Zn(2+) in the Golgi apparatus in live cells
por: Kowada, Toshiyuki, et al.
Publicado: (2021) -
Cryo-EM structures of human zinc transporter ZnT7 reveal the mechanism of Zn(2+) uptake into the Golgi apparatus
por: Bui, Han Ba, et al.
Publicado: (2023)