Quantitative single molecule analysis of podoplanin clustering in fibroblastic reticular cells uncovers CD44 function

Upon initial immune challenge, dendritic cells (DCs) migrate to lymph nodes and interact with fibroblastic reticular cells (FRCs) via C-type lectin-like receptor 2 (CLEC-2). CLEC-2 binds to the membrane glycoprotein podoplanin (PDPN) on FRCs, inhibiting actomyosin contractility through the FRC netwo...

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Detalles Bibliográficos
Autores principales: Lim, Shu En, Joseph, Megan D., de Winde, Charlotte M., Acton, Sophie E., Simoncelli, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170195/
https://www.ncbi.nlm.nih.gov/pubmed/37161290
http://dx.doi.org/10.1098/rsob.220377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170195/
https://www.ncbi.nlm.nih.gov/pubmed/37161290
http://dx.doi.org/10.1098/rsob.220377

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