T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases

BACKGROUND: Colorectal liver metastasis (CLM) is a leading cause of colorectal cancer mortality, and the response to immune checkpoint inhibition (ICI) in microsatellite-stable CRC has been disappointing. Administration of cytotoxic chemotherapy may cause increased density of tumor-infiltrating T ce...

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Detalles Bibliográficos
Autores principales: Høye, Eirik, Dagenborg, Vegar J, Torgunrud, Annette, Lund-Andersen, Christin, Fretland, Åsmund A, Lorenz, Susanne, Edwin, Bjørn, Hovig, Eivind, Fromm, Bastian, Inderberg, Else M, Greiff, Victor, Ree, Anne H, Flatmark, Kjersti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170408/
https://www.ncbi.nlm.nih.gov/pubmed/37161965
http://dx.doi.org/10.1093/gigascience/giad032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170408/
https://www.ncbi.nlm.nih.gov/pubmed/37161965
http://dx.doi.org/10.1093/gigascience/giad032

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