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Concurrent induction of apoptosis and necroptosis in apigenin‑treated malignant mesothelioma cells: Reversal of Warburg effect through Akt inhibition and p53 upregulation

A high dependence on aerobic glycolysis, known as the Warburg effect, is one of the metabolic features exhibited by tumor cells. Therefore, targeting glycolysis is becoming a very promising strategy for the development of anticancer drugs. In the present study, it was investigated whether pre-adapta...

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Detalles Bibliográficos
Autores principales: Lee, Yoon-Jin, Park, Kwan-Sik, Heo, Su-Hak, Cho, Moon-Kyun, Lee, Sang-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170486/
https://www.ncbi.nlm.nih.gov/pubmed/37083070
http://dx.doi.org/10.3892/or.2023.8548