Polytrimethylenimines: Highly Potent Antibacterial Agents with Activity and Toxicity Modulated by the Polymer Molecular Weight

[Image: see text] Cationic polymers have been extensively investigated as a potential replacement for traditional antibiotics. Here, we examined the effect of molecular weight (MW) on the antimicrobial, cytotoxic, and hemolytic activity of linear polytrimethylenimine (L-PTMI). The results indicate t...

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Detalles Bibliográficos
Autores principales: Pachla, Julita, Kopiasz, Rafał J., Marek, Gabriela, Tomaszewski, Waldemar, Głogowska, Agnieszka, Drężek, Karolina, Kowalczyk, Sebastian, Podgórski, Rafał, Butruk-Raszeja, Beata, Ciach, Tomasz, Mierzejewska, Jolanta, Plichta, Andrzej, Augustynowicz-Kopeć, Ewa, Jańczewski, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170506/
https://www.ncbi.nlm.nih.gov/pubmed/37093622
http://dx.doi.org/10.1021/acs.biomac.3c00139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170506/
https://www.ncbi.nlm.nih.gov/pubmed/37093622
http://dx.doi.org/10.1021/acs.biomac.3c00139

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