Insulin Activation Mediated by Uptake Mechanisms: A Comparison of the Behavior between Polymer Nanoparticles and Extracellular Vesicles in 3D Liver Tissues

[Image: see text] In this work, we compare the role of two different uptake mechanisms in the effectiveness of a nanoformulated drug, specifically insulin. Insulin is activated by interacting with insulin receptors exposed on the liver cell membrane that triggers the uptake and storage of glucose. T...

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Detalles Bibliográficos
Autores principales: Costagliola di Polidoro, Angela, Baghbantarghdari, Zahra, De Gregorio, Vincenza, Silvestri, Simona, Netti, Paolo Antonio, Torino, Enza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170511/
https://www.ncbi.nlm.nih.gov/pubmed/37023462
http://dx.doi.org/10.1021/acs.biomac.3c00102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170511/
https://www.ncbi.nlm.nih.gov/pubmed/37023462
http://dx.doi.org/10.1021/acs.biomac.3c00102

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