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Insulin Activation Mediated by Uptake Mechanisms: A Comparison of the Behavior between Polymer Nanoparticles and Extracellular Vesicles in 3D Liver Tissues
[Image: see text] In this work, we compare the role of two different uptake mechanisms in the effectiveness of a nanoformulated drug, specifically insulin. Insulin is activated by interacting with insulin receptors exposed on the liver cell membrane that triggers the uptake and storage of glucose. T...
Autores principales: | Costagliola di Polidoro, Angela, Baghbantarghdari, Zahra, De Gregorio, Vincenza, Silvestri, Simona, Netti, Paolo Antonio, Torino, Enza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170511/ https://www.ncbi.nlm.nih.gov/pubmed/37023462 http://dx.doi.org/10.1021/acs.biomac.3c00102 |
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