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Temporal resolution of NAIL-MS of tRNA, rRNA and Poly-A RNA is overcome by actinomycin D

RNA is dynamically modified and has the potential to respond to environmental changes and tune translation. The objective of this work is to uncover the temporal limitation of our recently developed cell culture NAIL-MS (nucleic acid isotope labelling coupled mass spectrometry) technology and overco...

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Detalles Bibliográficos
Autores principales: Hagelskamp, Felix, Borland, Kayla, Ammann, Gregor, Kaiser, Stefanie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170653/
https://www.ncbi.nlm.nih.gov/pubmed/37181633
http://dx.doi.org/10.1039/d2cb00243d