Self-oxidation of cysteine to sulfinic acid in an engineered T67C myoglobin: structure and reactivity

Myoglobin (Mb) was found to undergo self-oxidation when a cysteine residue was engineered at position 67 in the heme distal site. Both the X-ray crystal structure and mass spectrum confirmed the formation of a sulfinic acid (Cys–SO(2)H). Moreover, the self-oxidation could be controlled during protei...

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Detalles Bibliográficos
Autores principales: Dai, Wei, Yuan, Hong, Wang, Xiao-Juan, Gao, Shu-Qin, Tan, Xiangshi, Lin, Ying-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170655/
https://www.ncbi.nlm.nih.gov/pubmed/37181634
http://dx.doi.org/10.1039/d3cb00007a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170655/
https://www.ncbi.nlm.nih.gov/pubmed/37181634
http://dx.doi.org/10.1039/d3cb00007a

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