Computational analysis of missense variant CYP4F2*3 (V433M) in association with human CYP4F2 dysfunction: a functional and structural impact

BACKGROUND: Cytochrome P450 4F2 (CYP4F2) enzyme is a member of the CYP4 family responsible for the metabolism of fatty acids, therapeutic drugs, and signaling molecules such as arachidonic acid, tocopherols, and vitamin K. Several reports have demonstrated that the missense variant CYP4F2*3 (V433M)...

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Detalles Bibliográficos
Autores principales: Farajzadeh-Dehkordi, Mahvash, Mafakher, Ladan, Samiee-Rad, Fatemeh, Rahmani, Babak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170697/
https://www.ncbi.nlm.nih.gov/pubmed/37161313
http://dx.doi.org/10.1186/s12860-023-00479-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170697/
https://www.ncbi.nlm.nih.gov/pubmed/37161313
http://dx.doi.org/10.1186/s12860-023-00479-0

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