CRISPR-Cas9 knockout screen identifies novel treatment targets in childhood high-grade glioma

BACKGROUND: Brain tumours are the leading cause of cancer-related death in children, and there is no effective treatment. A growing body of evidence points to deregulated epigenetics as a tumour driver, particularly in paediatric cancers as they have relatively few genomic alterations, and key drive...

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Detalles Bibliográficos
Autores principales: Wenger, Anna, Karlsson, Ida, Kling, Teresia, Carén, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170782/
https://www.ncbi.nlm.nih.gov/pubmed/37161535
http://dx.doi.org/10.1186/s13148-023-01498-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170782/
https://www.ncbi.nlm.nih.gov/pubmed/37161535
http://dx.doi.org/10.1186/s13148-023-01498-6

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