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CRISPR-Cas9 knockout screen identifies novel treatment targets in childhood high-grade glioma
BACKGROUND: Brain tumours are the leading cause of cancer-related death in children, and there is no effective treatment. A growing body of evidence points to deregulated epigenetics as a tumour driver, particularly in paediatric cancers as they have relatively few genomic alterations, and key drive...
Autores principales: | Wenger, Anna, Karlsson, Ida, Kling, Teresia, Carén, Helena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10170782/ https://www.ncbi.nlm.nih.gov/pubmed/37161535 http://dx.doi.org/10.1186/s13148-023-01498-6 |
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