Cryptotanshinone Reverses Corticosteroid Insensitivity by Inhibition of Phosphoinositide-3-Kinase-δ in Chronic Obstructive Pulmonary Disease

PURPOSE: Corticosteroid insensitivity has become a major barrier in the treatment of chronic obstructive pulmonary disease (COPD). It is known that oxidative stress reduces the expression and activity of histone deacetylase (HDAC)-2 by activating phosphoinositide-3-kinase-δ(PI3Kδ)/Akt pathway, which...

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Detalles Bibliográficos
Autores principales: Xie, Tao, Huang, Rong, Deng, Daishuo, Tang, Peipei, Fu, Yufeng, Zheng, Yulong, Wan, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171224/
https://www.ncbi.nlm.nih.gov/pubmed/37180749
http://dx.doi.org/10.2147/COPD.S405757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171224/
https://www.ncbi.nlm.nih.gov/pubmed/37180749
http://dx.doi.org/10.2147/COPD.S405757

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