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Flurbiprofen inhibits heme induced NLRP3 inflammasome in Berkeley sickle cell disease mice
Sickle cell disease (SCD) is accompanied by several complications, which emanate from the sickling of erythrocytes due to a point mutation in the β-globin chain of hemoglobin. Sickled erythrocytes are unable to move smoothly through small blood capillaries and therefore, cause vaso occlusion and sev...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171431/ https://www.ncbi.nlm.nih.gov/pubmed/37180702 http://dx.doi.org/10.3389/fphar.2023.1123734 |