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Flurbiprofen inhibits heme induced NLRP3 inflammasome in Berkeley sickle cell disease mice

Sickle cell disease (SCD) is accompanied by several complications, which emanate from the sickling of erythrocytes due to a point mutation in the β-globin chain of hemoglobin. Sickled erythrocytes are unable to move smoothly through small blood capillaries and therefore, cause vaso occlusion and sev...

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Detalles Bibliográficos
Autores principales: Kour, Dilpreet, Ali, Mehboob, Khajuria, Parul, Sharma, Kuhu, Ghosh, Palash, Kaur, Sukhleen, Mahajan, Surbhi, Ramajayan, P., Bharate, Sonali S., Bhardwaj, Subhash, Sawant, Sanghapal D., Reddy, D. Srinivasa, Kumar, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171431/
https://www.ncbi.nlm.nih.gov/pubmed/37180702
http://dx.doi.org/10.3389/fphar.2023.1123734