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Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways

Sivelestat sodium (SIV), a neutrophil elastase inhibitor, is mainly used for the clinical treatment of acute respiratory distress syndrome (ARDS) or acute lung injury (ALI). However, studies investigating the effects of SIV treatment of ALI are limited. Therefore, this study investigated the potenti...

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Detalles Bibliográficos
Autores principales: Zhang, Hong, Zeng, Jun, Li, Jiankang, Gong, Huankai, Chen, Meiling, Li, Quan, Liu, Shengxing, Luo, Shanjun, Dong, Huanxiang, Xu, Yingke, Duan, Huanling, Huang, Ling, Lv, Chuanzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171443/
https://www.ncbi.nlm.nih.gov/pubmed/36724020
http://dx.doi.org/10.17305/bb.2022.8549