Cargando…

Sivelestat sodium attenuates acute lung injury by inhibiting JNK/NF-κB and activating Nrf2/HO-1 signaling pathways

Sivelestat sodium (SIV), a neutrophil elastase inhibitor, is mainly used for the clinical treatment of acute respiratory distress syndrome (ARDS) or acute lung injury (ALI). However, studies investigating the effects of SIV treatment of ALI are limited. Therefore, this study investigated the potenti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Hong, Zeng, Jun, Li, Jiankang, Gong, Huankai, Chen, Meiling, Li, Quan, Liu, Shengxing, Luo, Shanjun, Dong, Huanxiang, Xu, Yingke, Duan, Huanling, Huang, Ling, Lv, Chuanzhu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171443/ https://www.ncbi.nlm.nih.gov/pubmed/36724020 http://dx.doi.org/10.17305/bb.2022.8549

Ejemplares similares

The synergistic Reduning and cefmetazole sodium treatment of severe pneumonia is mediated by the AhR-Src-STAT3 pathway
por: Luo, Shanjun, et al.
Publicado: (2022)

Diosmetin Ameliorates Vascular Dysfunction and Remodeling by Modulation of Nrf2/HO-1 and p-JNK/p-NF-κB Expression in Hypertensive Rats
por: Meephat, Sariya, et al.
Publicado: (2021)

Advanced development and mechanism of sepsis-related acute respiratory distress syndrome
por: Gong, Huankai, et al.
Publicado: (2022)

Sodium Danshensu Cream Promotes the Healing of Pressure Ulcers in Mice through the Nrf2/HO-1 and NF-κB Pathways
por: Yang, Fei, et al.
Publicado: (2022)

Stevioside attenuates osteoarthritis via regulating Nrf2/HO-1/NF-κB pathway
por: Wu, Jia, et al.
Publicado: (2022)

Anti-Inflammatory Effect of Sulforaphane on LPS-Activated Microglia Potentially through JNK/AP-1/NF-κB Inhibition and Nrf2/HO-1 Activation
por: Subedi, Lalita, et al.
Publicado: (2019)

Inhibition of JNK Alleviates Chronic Hypoperfusion-Related Ischemia Induces Oxidative Stress and Brain Degeneration via Nrf2/HO-1 and NF-κB Signaling
por: Khan, Muhammad Sohail, et al.
Publicado: (2020)

Myocardial protective effect of sivelestat sodium in rat models with sepsis-induced myocarditis
por: Zhang, Rujun, et al.
Publicado: (2022)

Sivelestat sodium hydrate improves post-traumatic knee osteoarthritis through nuclear factor-κB in a rat model
por: Yu, Xiaofeng, et al.
Publicado: (2017)

Ginkgolide C slows the progression of osteoarthritis by activating Nrf2/HO-1 and blocking the NF-κB pathway
por: Ma, Tianwen, et al.
Publicado: (2022)

Renoprotective activity of sivelestat in severe acute pancreatitis in rats
por: WANG, HOUHONG, et al.
Publicado: (2013)

Garcinone E Mitigates Oxidative Inflammatory Response and Protects against Experimental Autoimmune Hepatitis via Modulation of Nrf2/HO-1, NF-κB and TNF-α/JNK Axis
por: Mohamed, Gamal A., et al.
Publicado: (2022)

Treatment with sivelestat sodium of acute respiratory distress syndrome induced by chemical pneumonitis: A report of three cases
por: Jing, Liang, et al.
Publicado: (2023)

Mangiferin Attenuates Myocardial Ischemia-Reperfusion Injury via MAPK/Nrf-2/HO-1/NF-κB In Vitro and In Vivo
por: Liu, Kun, et al.
Publicado: (2019)

Clinical Utility of the Sivelestat for the Treatment of ALI/ARDS: Moving on in the Controversy?
por: Ding, Qiongli, et al.
Publicado: (2022)

TLRs, NF-κB, JNK, and Liver Regeneration
por: Iimuro, Yuji, et al.
Publicado: (2010)

Mangiferin Alleviates Ovalbumin-Induced Allergic Rhinitis via Nrf2/HO-1/NF-κB Signaling Pathways
por: Piao, Chun Hua, et al.
Publicado: (2020)

Tranilast reduces cardiomyocyte injury induced by ischemia‑reperfusion via Nrf2/HO‑1/NF‑κB signaling
por: Wang, Wei, et al.
Publicado: (2023)

Evaluation of appropriate indications for the use of sivelestat sodium in acute respiratory distress syndrome: a retrospective cohort study
por: Maki, Chika, et al.
Publicado: (2019)

Trametenolic Acid Ameliorates the Progression of Diabetic Nephropathy in db/db Mice via Nrf2/HO-1 and NF-κB-Mediated Pathways
por: Duan, Qi, et al.
Publicado: (2022)

Stilbene glycoside protects osteoblasts against oxidative damage via Nrf2/HO-1 and NF-κB signaling pathways
por: Cheng, Jian, et al.
Publicado: (2018)

Piceatannol Attenuates Testosterone-Induced Benign Prostatic Hyperplasia in Rats by Modulation of Nrf2/HO-1/NFκB Axis
por: Eid, Basma G., et al.
Publicado: (2020)

Piceatannol SNEDDS Attenuates Estradiol-Induced Endometrial Hyperplasia in Rats by Modulation of NF-κB and Nrf2/HO-1 Axes
por: Binmahfouz, Lenah S., et al.
Publicado: (2022)

NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
por: Maeda, Shin
Publicado: (2010)

Propofol Induces the Expression of Nrf2 and HO-1 in Echinococcus granulosus via the JNK and p38 Pathway In Vitro
por: Luo, Guangyi, et al.
Publicado: (2023)

Molecular Mechanisms Underlying the Anti-Inflammatory Properties of (R)-(-)-Carvone: Potential Roles of JNK1, Nrf2 and NF-κB
por: Sousa, Cátia, et al.
Publicado: (2023)

Tanshinol ameliorates CCl(4)-induced liver fibrosis in rats through the regulation of Nrf2/HO-1 and NF-κB/IκBα signaling pathway
por: Wang, Rong, et al.
Publicado: (2018)

The evaluation of sivelestat sodium hydrate in acute lung injury/acute respiratory distress syndrome patients in the intensive care unit
por: Ikeda, T, et al.
Publicado: (2007)

Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1
por: Liao, Hai-han, et al.
Publicado: (2017)

Sappanone A Alleviated IL-1β-Induced Inflammation in OA Chondrocytes through Modulating the NF-κB and Nrf2/HO-1 Pathways
por: Zhang, Zhi, et al.
Publicado: (2022)

Efficacy and safety of sivelestat sodium for the treatment of inflammatory response in acute Stanford type A aortic dissection: a retrospective cohort study
por: Zhou, Yan, et al.
Publicado: (2022)

Scrophularia koraiensis Nakai Attenuates Allergic Airway Inflammation via Suppression of NF-κB and Enhancement of Nrf2/HO-1 Signaling
por: Jung, Tae-Yang, et al.
Publicado: (2020)

Cerevisterol Alleviates Inflammation via Suppression of MAPK/NF-κB/AP-1 and Activation of the Nrf2/HO-1 Signaling Cascade
por: Alam, Md Badrul, et al.
Publicado: (2020)

Betulin Alleviates the Inflammatory Response in Mouse Chondrocytes and Ameliorates Osteoarthritis via AKT/Nrf2/HO-1/NF-κB Axis
por: Ren, Chenghao, et al.
Publicado: (2021)

Epigallocatechin Gallate Protects against Hypoxia-Induced Inflammation in Microglia via NF-κB Suppression and Nrf-2/HO-1 Activation
por: Kim, So-Ra, et al.
Publicado: (2022)

Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO-1 and inhibiting the NF-κB signaling pathway
por: Sun, Weichao, et al.
Publicado: (2022)

Antihepatocarcinoma Effect of Portulaca oleracea L. in Mice by PI3K/Akt/mTOR and Nrf2/HO-1/NF-κB Pathway
por: Guoyin, Zheng, et al.
Publicado: (2017)

Protective Effects of Pterostilbene on Lipopolysaccharide-Induced Acute Lung Injury in Mice by Inhibiting NF-κB and Activating Nrf2/HO-1 Signaling Pathways
por: Zhang, Yong, et al.
Publicado: (2021)

The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats
por: Li, Guofu, et al.
Publicado: (2016)

Corrigendum to “Myricetin Possesses Potential Protective Effects on Diabetic Cardiomyopathy through Inhibiting IκBα/NFκB and Enhancing Nrf2/HO-1”
por: Liao, Hai-han, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rkjgaaqg967fdhhd0qjsr942kh