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Genome-wide analysis of RNA-binding proteins co-expression with alternative splicing events in mitral valve prolapse

OBJECTIVES: We investigated the role and molecular mechanisms of RNA-binding proteins (RBPs) and their regulated alternative splicing events (RASEs) in the pathogenesis of mitral valve prolapse (MVP). METHODS: For RNA extraction, we obtained peripheral blood mononuclear cells (PBMCs) from five patie...

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Detalles Bibliográficos
Autores principales: Zhao, Meng, Zhou, Jingxin, Tang, Yihu, Liu, Mingzhu, Dai, Yawei, Xie, Hui, Wang, Zihao, Chen, Liang, Wu, Yanhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171460/
https://www.ncbi.nlm.nih.gov/pubmed/37180137
http://dx.doi.org/10.3389/fimmu.2023.1078266