Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy

The main carcinogen for keratinocyte skin cancers (KCs) such as basal and squamous cell carcinomas is ultraviolet (UV) radiation. There is growing evidence that accumulation of mutations and clonal expansion play a key role in KC development. The relationship between UV exposure, epidermal mutation...

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Detalles Bibliográficos
Autores principales: Wong, Ho Yi, Lee, Ruby C., Chong, Sharene, Kapadia, Stuti, Freeman, Michael, Murigneux, Valentine, Brown, Susan, Soyer, H. Peter, Roy, Edwige, Khosrotehrani, Kiarash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171798/
https://www.ncbi.nlm.nih.gov/pubmed/37163607
http://dx.doi.org/10.1126/sciadv.adf2384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171798/
https://www.ncbi.nlm.nih.gov/pubmed/37163607
http://dx.doi.org/10.1126/sciadv.adf2384

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