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Epidermal mutation accumulation in photodamaged skin is associated with skin cancer burden and can be targeted through ablative therapy
The main carcinogen for keratinocyte skin cancers (KCs) such as basal and squamous cell carcinomas is ultraviolet (UV) radiation. There is growing evidence that accumulation of mutations and clonal expansion play a key role in KC development. The relationship between UV exposure, epidermal mutation...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171798/ https://www.ncbi.nlm.nih.gov/pubmed/37163607 http://dx.doi.org/10.1126/sciadv.adf2384 |