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Phosphorylation-dependent recognition of diverse protein targets by the cryptic GK domain of MAGI MAGUKs

Dynamic signal transduction requires the rapid assembly and disassembly of signaling complexes, often mediated by phosphoprotein binding modules. The guanylate kinase-like (GK) domain of the membrane-associated guanylate kinases (MAGUKs) is such a module orchestrating signaling at cellular junctions...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Cao, Aili, Lin, Lin, Chen, Ying, Shang, Yuan, Wang, Chao, Zhang, Mingjie, Zhu, Jinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171801/
https://www.ncbi.nlm.nih.gov/pubmed/37163606
http://dx.doi.org/10.1126/sciadv.adf3295