7SK methylation by METTL3 promotes transcriptional activity

A fundamental feature of cell signaling is the conversion of extracellular signals into adaptive transcriptional responses. The role of RNA modifications in this process is poorly understood. The small nuclear RNA 7SK prevents transcriptional elongation by sequestering the cyclin dependent kinase 9/...

Descripción completa

Detalles Bibliográficos
Autores principales: Perez-Pepe, Marcelo, Desotell, Anthony W., Li, Hengyi, Li, Wenxue, Han, Bing, Lin, Qishan, Klein, Daryl E., Liu, Yansheng, Goodarzi, Hani, Alarcón, Claudio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171809/
https://www.ncbi.nlm.nih.gov/pubmed/37163588
http://dx.doi.org/10.1126/sciadv.ade7500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171809/
https://www.ncbi.nlm.nih.gov/pubmed/37163588
http://dx.doi.org/10.1126/sciadv.ade7500

Ejemplares similares