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Single-domain antibody–based noninvasive in vivo imaging of α-synuclein or tau pathology

Intracellular deposition of α-synuclein and tau are hallmarks of synucleinopathies and tauopathies, respectively. Recently, several dye-based imaging probes with selectivity for tau aggregates have been developed, but suitable imaging biomarkers for synucleinopathies are still unavailable. Detection...

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Detalles Bibliográficos
Autores principales: Jiang, Yixiang, Lin, Yan, Krishnaswamy, Senthilkumar, Pan, Ruimin, Wu, Qian, Sandusky-Beltran, Leslie A., Liu, Mengyu, Kuo, Min-Hao, Kong, Xiang-Peng, Congdon, Erin E., Sigurdsson, Einar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171817/
https://www.ncbi.nlm.nih.gov/pubmed/37163602
http://dx.doi.org/10.1126/sciadv.adf3775